Retatrutide

Retatrutide is a synthetic triple-agonist peptide targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors, engineered with a C20 fatty diacid moiety for extended plasma half-life. It is utilized in in vitro biochemical research to investigate energy homeostasis pathways, adipocyte lipolysis mechanisms, and multi-receptor incretin signaling associated with metabolic modulation.